Other than having one lifter in a Shovelhead go bad years ago I never had one since, but like Chopper says, if you are there and changing cam why not put lifters in, they are cheap and you are tore down, I would, but then again I don't really worry about what things cost if I am in that area doing work it gets replaced regardless, if it needs it or not who knows, but why find out you gotta go back in later. Smitty, I understand what you say about how many miles on your bikes, but we all know not everyone has the same experience, guy in our HOG chapter has a SE Ultra, 2007 that has engine problems, bike is always serviced at the dealer when it should be, and they are covering it under warranty, point is that even though you do maintenance when you should things still can happen. His bike only has about 20K miles on it also.